Discoidin Domain Receptor Inhibitors

DDR1

DDR2

Discoidin Domain Receptor Inhibitors, Degraders & Ligands

Product Name	DDR1	DDR2	Purity
Sitravatinib	DDR1, IC₅₀: 29 nM	DDR2, IC₅₀: 0.5 nM	99.57%
GLPG3312	DDR1, IC₅₀: 57 nM		98.63%
WRG-28		DDR2, IC₅₀: 230 nM	99.76%
Anti-Mouse DDR2 Antibody (DAB0065)		DDR2
VU6015929	DDR1, IC₅₀: 4.67 nM	DDR2, IC₅₀: 7.39 nM	99.50%
DDR1-IN-4	DDR1, IC₅₀: 29 nM	DDR2, IC₅₀: 1900 nM	98.19%
Collagen (bovine skin)	DDR1	DDR2
FGFR1/DDR2 inhibitor 1		DDR2, IC₅₀: 3.2 nM	98.26%
DDR1-IN-6	DDR1, IC₅₀: 9.72 nM		98.02%
DDR1/2 inhibitor-2	DDR1	DDR2	99.73%
DDR1-IN-5	DDR1, IC₅₀: 7.36 nM		99.65%
DDR1-IN-1 dihydrochloride	DDR1, IC₅₀: 105 nM	DDR2, IC₅₀: 413 nM	98.92%
SR-302	DDR1, IC₅₀: 23 nM	DDR2, IC₅₀: 18 nM	98.51%
CIDD-8633		DDR2, IC₅₀: 6.105 μM
Sitravatinib malate	DDR1, IC₅₀: 29 nM	DDR2, IC₅₀: 0.5 nM
Axl-IN-21	DDR1, IC₅₀: 22.2 nM
ML786 dihydrochloride		DDR2, IC₅₀: 7.0 nM
AP4-43	DDR1
DDR1/2 IN-4	DDR1, pKi: 8.6	DDR2, pKi: 8.2
DDR2-IN-2		DDR2
SJ11646	DDR1
DDR1-IN-11	DDR1, IC₅₀: 46.16 nM
DDR1-IN-8	DDR1	DDR2
DDR1/2 inhibitor-3	DDR1, IC₅₀: 9.4 nM	DDR2, IC₅₀: 20.4 nM

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